TABLE 4.
Field laboratory tests as Campylobacter diagnostic modalitiesa
| Finding | Sensitivity (%) | Specificity (%) | NPV (%) | PPV (%) | LR+ | LR− | AUC |
|---|---|---|---|---|---|---|---|
| Fecal leukocytes | |||||||
| Any positive | 45 (35, 55) | 65 (52, 76) | 44 (34, 54) | 66 (53, 77) | 1.3 (0.9, 1.9) | 0.9 (0.7, 1.1) | 0.57 (0.48, 0.66) |
| ≥1-5/HPF | 34 (25, 44) | 82 (70, 90) | 45 (36, 54) | 73 (58, 85) | 1.8 (1.0, 3.3) | 0.8 (0.7, 1.0) | |
| Lactoferrin latex agglutination | |||||||
| Any positive | 96 (91, 99) | 48 (36, 60) | 89 (73, 96) | 75 (67, 82) | 1.9 (1.5, 2.3) | 0.1 (0.1, 0.2) | 0.80 (0.73, 0.87) |
| ≥2+ | 91 (84, 95) | 58 (46, 70) | 80 (65, 89) | 78 (70, 85) | 2.2 (1.6, 2.9) | 0.2 (0.1, 0.3) | |
| Serum CRP | 89 (79, 95) | 69 (51, 83) | 75 (56, 88) | 85 (75, 92) | 2.8 (1.7, 4.6) | 0.1 (0.1, 0.2) | 0.83 (0.75, 0.91) |
| Campylobacter EIA | 95 (88, 98) | 94 (84, 98) | 91 (81, 96) | 96 (90, 99) | 16 (6.0, 40) | 0.1 (0.1, 0.2) | 0.94 (0.89, 0.98) |
| Campylobacter PCR | 82 (65, 92) | 90 (72, 97) | 79 (61, 90) | 91 (75, 98) | 7.9 (2.7, 23) | 0.2 (0.1, 0.4) | 0.86 (0.76, 0.95) |
| Campylobacter-specific ASCs | 46 (55, 74) | 60 (42, 76) | 38 (25, 52) | 68 (52, 81) | 1.2 (0.7, 1.9) | 0.9 (0.6, 1.3) | 0.53 (0.41, 0.65) |
a
Abbreviations: NPV, negative predictive value; PPV, positive predictive value; LR+, positive likelihood ratio; LR−, negative likelihood ratio; AUC, area under the ROC curve (AUC values represent true positive rate/true negative rate ratios); HPF, high-power field. The data in parentheses are 95% confidence intervals.