TABLE 3.

Putative CD8 and CD4 epitopes containing mutations and amino acid and codon changes for these epitopes in animals 4 and 5^a

Epitope	Gag peptide(s)	Epitope-containing sequence	Amino acid change			Codon change
			Position	From	To	Position	From	To
Animal 4
CD8 epitopes
Original	10, 11	LDRFGLAESLL	46	L	I	671	TTA	ATA
			48	E	D	679	GAA	GAC
	107, 108	DRQAGFLGLGP	429	D	E	1822	GAC	GAA
			432	A	V	1830	GCG	GTG
New	25, 26	KQIVQRHLVVE	101	K	R	837	AAA	AGA
	35, 36	GGNYVHLPLSP	145	V	I	968	GTC	ATC
CD4 epitopes
Original	None
New	25, 26	KQIVQRHLVVE	101	K	R	837	AAA	AGA
	97	RGPRKPIKCWNCGKE	385	R	K	1689	AGG	AAG
Animal 5
CD8 epitopes
Original	35, 36	GGNYVHLPLSP	145	V	A	969	GTC	GCC
New	101	HSARQCRAPRRQGCW	402	S	P	1739	TCT	CCT
					L	1739, 1740		CTT
CD4 epitopes
Original	None
New	15	CQKILSVLAPLVPTG	59	K	R	711	AAA	AGA
	101	HSARQCRAPRRQGCW	402	S	P	1739	TCT	CCT
					L	1739, 1740		CTT

^aChanges are in boldface.