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Abilities of beta-E6 proteins to activate telomerase and interact with required cellular proteinsa
| E6 protein | Extension of life span | TRAP activity | hTERT mRNA induction | Interacts with E6AP | Interacts with NFX1-91 |
|---|---|---|---|---|---|
| LXSN | − | − | − | − | − |
| HPV5 | + | − | +/− | − | − |
| HPV8 | ++ | + | +/− | + | − |
| HPV20 | − | − | − | − | − |
| HPV38 | +++ | ++ | ++ | ++ | ++ |
| HPV16 | ++++ | +++ | +++ | ++++ | ++ |
−, no detectable activity; the number of + symbols indicates the relative level of activity in each assay.
