TABLE 3.
Monkey no. | Titer at indicated time pointb
|
||||||
---|---|---|---|---|---|---|---|
Day of ΔV1ΔV2 inoculationb | Wk 8 p.i. | Wk 28 p.i. | Day of SIV239 challengec | Wk 2 p.c. | Wk 12 p.c. | Wk 26 p.c. | |
Mm 379-89 | Negative | 1:160 | 1:80 | 1:80 | 1:120 | 1:60 | 1:80 |
Mm 535-99 | Negative | 1:25 | Negative | Negative | Negative | Negative | Negative |
Mm 536-99 | Negative | 1:640 | 1:140 | 1:240 | 1:240 | 1:2,240 | 1:4,480 |
Mm 117-93 | 1:320 | 1:560 | 1:480 | 1:1,120 | 1:1,120 | 1:640 | 1:1,920 |
Mm 526-99 | Negative | 1:25 | Negative | Negative | Negative | 1:800 | 1:2,560 |
Mm 139-99 | Negative | Negative | Negative | Negative | Negative | 1:2,560 | >1:5,120 |
Mm 322-92 | ND | ND | ND | Negative | Negative | 1:1,280 | 1:2,560 |
Mm 333-95 | ND | ND | ND | Negative | Negative | 1:1,280 | 1:4,480 |
Mm 39-01 | ND | ND | ND | Negative | Negative | Negative | ND |
Dilutions that yielded 50% neutralization are shown. Different pools of SIV+ rhesus monkey plasma gave titers of 1:1,920 to 1:5,120 when tested in parallel with these assays. p.i., postinoculation; p.c., after WT SIV239 challenge; ND, not done.
16 July 2002.
9 April 2003.