FIG. 2.

Env-specific proliferation responses of vaccinated ponies. (A) Proliferation against a comprehensive Env peptide pool spanning the entire EV0 gp90 sequence was tested against DOC PBMC from vaccinated ponies in a thymidine incorporation assay. An SI of 2.5 was the cutoff for a positive response. (B) Thymidine incorporation was used to measure the proliferation of DOC PBMC from the 21 EIAV_D9-vaccinated ponies in response to peptides indicated by the matrix pools. Variant peptides are shown in italics, and conserved peptides are shown in bold. Shaded blocks identify ponies with positive proliferation (SI > 2.5) in response to specific peptides.