TABLE 1.
Summary of EIAVD9-vaccinated ponies
| Pony | Sex | Age (yr) | MHC I allele | MHC II allele
|
Time of acute disease (days postchallenge) | |
|---|---|---|---|---|---|---|
| DRA | DQA | |||||
| EV0-challenged ponies | ||||||
| A27 | F | 7 | A9/W11 | 101/101 | NDa | |
| C27 | F | 5 | W11/W11 | 101/JBH11 | 301/1501/1301b | |
| C28 | F | 5 | A10/A10 | 101/101 | 301/1301 | 49 |
| C34 | F | 5 | A8/A10 | 101/201 | 201/201 | |
| E31 | M | 3 | A1/A3 | 101/101 | 301/401 | |
| E33 | M | 3 | A9/A9 | 101/101 | 701/701 | |
| E34 | F | 3 | A1/A9 | 101/JBH11 | 301/1201/1301b | |
| E35 | F | 3 | A1/A1 | 201/JBH11 | 301/701 | |
| EV6-challenged ponies | ||||||
| 558 | M | 12 | A2/A9 | 101/301 | 301/1301 | 113 |
| A32 | F | 7 | A9/A9 | 101/301 | 301/1301 | |
| A33 | M | 7 | A9/A9 | 101/101 | 301/401/1301b | 4 |
| C29 | M | 5 | A3/A9 | 101/101 | 701/701 | |
| C33 | F | 5 | A1/A1 | 201/JBH11 | 1001/1201 | |
| C36 | M | 5 | A1/A1 | 101/JBH11 | 301/1201 | 47 |
| D31 | M | 4 | A2/A9 | 101/101 | 301/301 | |
| D44 | M | 4 | A2/A9 | 101/301 | 301/1501 | |
| EV13-challenged ponies | ||||||
| 886 | F | 9 | A5/A6 | 101/101 | 1301/1301 | 70 |
| B22 | M | 6 | NDa | 101/101 | 301/401 | 14 |
| B27 | M | 6 | A5/A6 | 101/101 | 1101/1101 | 36 |
| D34 | M | 4 | A5/A9 | 201/201 | 701/1001/1301b | |
| D38 | M | 4 | A2/A3 | 101/101 | 1501/1501 | 85 |
| D39 | M | 4 | A1/A2 | 101/201 | 201/201 | 17 |
| D40 | M | 4 | A2/A2 | 101/101 | 601/1501 | |
| E30 | M | 3 | A9/W11 | 101/101 | 301/301 | |
a
Due to insufficient PBMC, MHC typing was not performed.
b
Having three MHC II sequences, including the 1303 allele, for DQA is not uncommon. See reference 20.