TABLE 1.

Numbers of genes up- or downregulated in D. vulgaris wild-type cells grown under different conditions^a

COG functional category	No. of genes up- or down-regulated for growth condition
	CP vs 50%, up	CP vs 50%, down	CP vs 5%, up	CP vs 5%, down	CP vs H2, up	CP vs H2, down	CP vs lactate, up	CP vs lactate, down
i, translation, ribosomal structure, and biogenesis	4	21	3	1	0	1	15	2
ii, RNA processing and modification	0	0	0	0	0	0	0	0
iii, transcription	5	4	3	1	2	0	4	4
iv, DNA replication, recombination, and repair	1	2	0	0	0	0	5	2
v, cell division and chromosome partitioning	2	1	0	1	0	0	1	1
vi, defense mechanisms	3	0	0	0	0	0	3	0
vii, posttranslational modification, protein turnover, chaperones	6	6	0	0	0	0	4	11
viii, cell envelope biogenesis, outer membrane	9	5	3	3	3	1	6	12
ix, cell motility and secretion	14	3	9	0	5	0	1	6
x, signal transduction mechanisms	13	10	3	7	4	2	16	16
xi, extracellular structures	0	0	0	0	0	0	0	0
xii, intracellular trafficking, secretion, and vesicular transport	2	2	0	0	0	0	0	1
xiii, energy production and conversion	22	21	11	20	7	7	17	29
xiv, carbohydrate transport and metabolism	0	6	0	2	0	0	5	6
xv, amino acid transport and metabolism	19	22	7	6	6	3	10	15
xvi, nucleotide transport and metabolism	1	3	0	0	0	0	2	1
xvii, coenzyme metabolism	7	3	3	1	3	0	10	3
xviii, lipid metabolism	0	1	0	0	0	0	1	1
xix, inorganic ion transport and metabolism	5	11	4	4	2	4	7	8
xx, secondary metabolites biosynthesis, transport, and catabolism	1	0	1	0	0	0	1	0
xxi, general function prediction only	13	12	5	4	5	2	12	20
xxii, function unknown	73	55	24	37	19	20	63	79
Overallb	198	188	78	89	56	40	193	229

^aCP, 50%, 5%, and lactate indicate cells grown in WP medium with cathodic hydrogen, 50% (vol/vol) hydrogen, 5% (vol/vol) hydrogen, or lactate as the electron donor for sulfate reduction, respectively. “Up” and “down” indicate up- and down-regulation, respectively.

^bThe overall total does not count genes belonging to multiple categories more than once.