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. 2008 Feb 1;190(7):2572–2579. doi: 10.1128/JB.01248-07

FIG. 1.

FIG. 1.

Iterative assembly process schema. Each iteration of the assembly process consists of the following steps. (Step 1) Nucleotide similarities between environmental reads and seed sequences are computed, and highly similar reads are selected. (Step 2) Paired reads are recruited, along with the highly similar reads. (Step 3) Both similar and paired reads are subjected to the assembly process. (Step 4) The resulting contigs are screened both for length and coverage, and those selected are used as seed sequences for the next iteration.