TABLE 1.
Cholate derivatives induce colony formation by C. difficile spores
| Cholate derivative added to BHISa | CFU recovery (%)b
|
|
|---|---|---|
| Mean | SD | |
| TA | 100 | |
| GA | 86.3 | 17.2 |
| CA | 75.1 | 10.3 |
| CDCA | <0.0001c | |
| UA | <0.0001c | |
a
Spores were serially diluted and spread on BHIS agar containing 0.1% taurocholate (TA), glycocholate (GA), cholate (CA), chenodeoxycholate (CDCA), or ursodeoxycholate (UA).
b
Data are percentages relative to the value obtained with BHIS(TA) and are means of three independent experiments.
c
CFU for CDCA and UA were below the limit of detection for this experiment.