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An MCP-minus mutant is subject to increased DNA damage during metabolism of 1,2-PD
| Trial | No. of His+ revertants of BE966 in wild-type S. enterica
|
% Change | No. of His+ revertants of BE966 in MCP-minus mutant (ΔpduA)
|
% Change | ||
|---|---|---|---|---|---|---|
| Without 1,2-PD | With 1,2-PD | Without 1,2-PD | With 1,2-PD | |||
| 1 | 69 ± 5 | 65 ± 5 | −6 | 67 ± 7 | 92 ± 7 | +37 |
| 2 | 95 ± 3 | 84 ± 4 | −12 | 91 ± 10 | 109 ± 10 | +20 |
| 3 | 134 ± 8 | 130 ± 15 | −3 | 76 ± 5 | 92 ± 5 | +21 |
