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. Author manuscript; available in PMC: 2009 Mar 7.
Published in final edited form as: J Mol Biol. 2008 Jan 5;376(5):1360–1376. doi: 10.1016/j.jmb.2007.12.063

Table 4.

Binding affinities of wild-type and substituted LUSH proteins for alcohols.

Wild-type T57S S52A T57A
Ethanol 107 ± 13 mM * * *
Butanol 11 ± 1 mM 16 ± 2 mM 158 ± 54 mM >> 200mM
Pentanol 2 ± 0.3 mM 2 ± 0.3 mM 6 ± 0.9 mM
Hexanol 0.20 ± 0.02 µM
*

Indicates that no alcohol could compete for binding of ANS at any of the concentrations tested