TABLE 1.

Anomalous resistance to HSV-1 in TNFR knockout strains

HSV-1(17+) doseb	Mortality rate (%)a for:
	C57BL/6	p55−/− N5	p75−/− N5	p55−/− p75−/− N4
0.1×	0	20	0	0
1×	0	50	0	0
10×	6	80	13	14

^aNumber of mice for each group varied from 5 (0.1× and 1× experiments) to 13 (10× experiments). The percentage of mortality is based on combined results from five experiments.

^bViral dose indicated (×) is based on LD₅₀ determined previously for p55^−/− N5 mice to be 320 PFU. LD₅₀ for C57BL/6 is > 10⁵ PFU.