FIG. 8.

Comparison of the gene transfer and cell-binding profiles of Ad5 vectors. (A) Transduction of 293 and 293.CD40 cells with Ad5Luc1, Ad5Luc.FF/CD40L, or Ad5Luc.FF/CD40L.F5Δ was done essentially as described in the legend to Fig. 6, except that no inhibition of infection was attempted. (B) Radiolabeled viruses were allowed to bind to cells under conditions which prevented their internalization. After unbound virus was removed, the cell-associated radioactivity was measured with a scintillation counter. All of the measurements were done in triplicate. part/cell, particles per cell.