FIG. 3.
Relative expression of VZV genes during lytic infection. The VZV genome consists of unique long (UL) and short (US) segments, each bounded by terminal and internal inverted repeated DNA sequences (TRL/IRL and IRs/TRs). Transcription of VZV genes was determined during lytic virus growth in cell culture (Fig. 2), and relative expression of virus genes was assessed (Table 3). The relative size, direction of transcription, and expression of each of the 71 predicted virus ORFs show that the most abundant transcripts (ORFs 9, 33, 49, 63/70, and 64/69) mapped across the virus genome.