TABLE 2.
Marker | No. of expt | Age (mo) | Mean fluorescence intensityb ± SEM | Pc |
---|---|---|---|---|
MHC class II | 16 | 2-4 | 1.5 ± 0.1 | <0.001 |
CD40 | 8 | 2-4 | 1.4 ± 0.1 | 0.042 |
B7-2 | 13 | 2-4 | 1.2 ± 0.1 | 0.041 |
MHC class I | 10 | 2-4 | 1.2 ± 0.06 | 0.006 |
CD11b | 13 | 2-4 | 0.6 ± 0.25 | 0.012 |
FACS analysis. Each experiment was done with pooled sex-matched transgenic (n = 3) and control nontransgenic (n = 3) littermates.
The data are expressed as the ratio of nontransgenic to transgenic DC.
Student's t test for single samples.