Table 2. Solicited adverse events after primary and booster YF-17D vaccination.
| Adverse event | Primary vaccination (N = 155) | Booster vaccination (N = 20) | ||||
| Intradermal | Subcutaneous | Intradermal | Subcutaneous | |||
| Local | Erythema | N yes (%) | 63 (82) | 25 (32) | 6 (60) | 1 (10) |
| Mean N days (s.e.m.) | 4·3 (±0·5) | 1·1 (±0·2) | 3·2 (±1·0) | 1·0 (±0·9) | ||
| Swelling | N yes (%) | 52 (68) | 9 (12) | 6 (60) | 0 (0) | |
| Mean N days (s.e.m.) | 2·6 (±0·4) | 0·3 (±0·1) | 2·6 (±0·9) | - | ||
| Pain | N yes (%) | 6 (8) | 15 (19) | 2 (20) | 0 (0) | |
| Mean N days (s.e.m.) | 0·1 (±0·06) | 0·6 (±0·2) | 0·2 (±0·1) | - | ||
| Severity | N +/− (mild) | 39 | 15 | 3 | - | |
| N + (moderate) | 24 | 9 | 2 | 2 | ||
| N ++ (severe) | - | 1 | - | |||
| Systemic | Myalgia | N yes (%) | 12 (16) | 27 (22) | 1 (10) | 1 (10) |
| Mean N days (s.e.m.) | 0·4 (±0·1) | 0·7 (±0·1) | 0·1 (±0·1) | 0·7 (±0·7) | ||
| Fever | N yes (%) | 4 (5) | 8 (10) | 0 (0) | 0 (0) | |
| Mean N days (s.e.m.) | 0·1 (±0·03) | 0·2 (±0·06) | - | - | ||
| Severity | N +/− (mild) | 9 | 17 | - | - | |
| N + (moderate) | 3 | 8 | 1 | 1 | ||
| N ++ (severe) | - | 2 | - | - | ||
Safety of vaccination expressed in various parameters. Severity of adverse events could be graded with - (absent), +/− (mild), + (moderate) and ++ (severe). S.e.m. = standard error of the mean.