FIG. 5.

Nckβ colocalizes with Dab1 in process termini after Reelin stimulation. (A to C) Nckβ (green; A and C) is predominantly found in the soma of primary neurons from Reelin mutant animals fixed after 10-min treatments with control conditioned medium, while Dab1 (red; B and C) was found throughout the neuron. Colocalization between Nckβ and Dab1 was observed in the cell soma but not in the processes (yellow; C). (D to F) After treatment with Reelin-conditioned medium for 10 min prior to fixation, Nckβ (D and F) was detected in processes with Dab1 (E and F), and colocalization (F) was apparent near the process termini. Bar, 20 μm.