Table 4.
Comparison of 1H NMR spectra data (δ, CDCl3) of sterone X and 4α-methyl-fecosterone
| Assignment | Chemical shift
|
|
|---|---|---|
| 4α-Methyl-24,25-epoxy-cholesta-7- en-3-one (sterone X) | 4α-Methyl-fecosterone | |
| H-2α | 2.45 (ddd, J = 13.97, 13.97, 6.62 Hz) | 2.45 (ddd, J = 14.71, 14.71, 6.62 Hz) |
| H-2β | 2.35 (unresolved ddd) | 2.34 (ddd, J = 14.71, 5.15, 2.2 Hz) |
| H-4β | 2.30 (unresolved dq) | 2.29 (unresolved dq) |
| C-4α-CH3 | 1.00 (d, J = 6.62 Hz) | 1.01 (d, J = 7.36 Hz) |
| H-7 | 5.32 (m) | — |
| H-9 | 2.67 (dd, J = 6.62, 6.62 Hz) | — |
| H-19 | 1.17 (s) | 1.18 (s) |
| H-18 | 0.62 (s) | 0.62 (s) |
| H-21 | 0.94 (d, J = 6.62 Hz) | 0.94 (d, J = 6.62 Hz) |
| H-24 | 2.33 (t, J = 7.35 Hz) | — |
| C-24-exo-methylene | — | 4.67, 4.64 (d, J = 1.5 Hz) |
| H-25 | — | 2.21 (septet, J = 7.35 Hz) |
| H-26, H-27 | 1.29 (s), 1.25 (s) | 1.00 (d, J = 6.62 Hz) |