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. 1999 Oct 26;96(22):12685–12690. doi: 10.1073/pnas.96.22.12685

Figure 2.

Figure 2

Lipid efflux study of kindred. (A) Lipid efflux from normal control fibroblast cells (open columns) and proband fibroblast (subject VII-1) (lined columns) was measured, using cholesterol-labeled cells (columns A-C) or phospholipid-labeled cells (column D), with either 100 μg/ml HDL (column A), 10 μg/ml apoA-I (columns B and D), or 10 μg/ml apoA-II (column C) as the acceptor. Results for control cells are the mean percent efflux ± SD from three normal cell lines. Results of the proband are the mean percent efflux ± SD of triplicate determinations. (B) Lipid efflux of kindred. Normal cells (column A), and cells from subjects VI-3 (column B), VII-1 (column C), and VII-2 (column D) were radiolabeled with cholesterol and incubated with 10 μg/ml apoA-I. Effux from control cells is the mean percent efflux ± SD from three normal cell lines. Results for the subjects from the kindred are the mean percent efflux ± SD of triplicate determinations.