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. 1997 Aug 19;94(17):9131–9135. doi: 10.1073/pnas.94.17.9131

Table 1.

Sequence variation of mtDNA and mtDNA-encoded polypeptides in Hominoidea

Comparison Nucleotide differences
Amino acid differences*
Promoters 12S rRNA 16S rRNA tRNAs I III IV V
European–Japanese 0 3 3 0 0 0 0 0
European–African 0 6 5 5 0 0 0 0
European–common chimp 2 35 81 59 102 22 19 16
European–pigmy chimp 2 30 95 57 99 24 17 15
European–gorilla 2 33 116 89 127 21 26 21
European–orangutan 4 81 164 155 265 38 54 54
Common chimp–pigmy chimp 2 11 37 31 60 15 5 12
Common chimp–gorilla 1 40 104 89 143 27 22 30
Common chimp–orangutan 6 87 157 153 285 41 53 59

The table, modified from Horai et al. (9), shows a comparison between human mtDNA (European, Japanese, and African) and nonhuman primate mtDNA (common chimpanzee, pigmy chimpanzee, gorilla, and orangutan). Data are derived from sequences deposited in GeneBank (9, 31). 

*

Amino acid substitutions that have been described as polymorphic in humans (32) were excluded from the analysis. Different subunits of the same oxidative phosphorylation complex (I–V) were pooled. 

Promoter regions (33) correspond to human mtDNA positions 396–411 (light-strand promoter) and 554–568 (major heavy-strand promoter).