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Platelet cAMP and PLA2 levels
| Subject | cAMP, nmol per mg of protein
|
Thrombin-induced cAMP decrease, % | Platelet PLA2, pmol hydrolyzed per 108 platelets
|
||
|---|---|---|---|---|---|
| Basal | Iloprost (10 nM) | Cytosol | Membrane | ||
| Normal | 3.3 ± 1.1 (6) | 28.8 ± 11.6 (6) | 41.2 ± 16.2 (6) | 666 ± 303 (9) | 121 ± 48 (9) |
| Patient | 2.5 ± 1.0 (3) | 22.4 ± 10.9 (3) | 66 (2) | 1,064 | 128 |
Results are shown mean ± SD. Numbers in parenthesis indicate the number of normal subjects studied or the number of studies in the patient.
