Skip to main content
. 2008 Feb 29;8:65. doi: 10.1186/1471-2407-8-65

Table 2.

Cell cycle distributions after 24 h incubation with equitoxic concentrations of VRL and VFL.

Cell line Contr 60 nM VFL Equitoxic conc. VRL 150 nM VFL Equitoxic conc. VRL
% G1
ECV304 39.1 ± 1.9 36.3 ± 2.2 (10 nM) 38.6 ± 2.8 15.0 ± 3.4a (30 nM) 10.1 ± 1.6a
CAL-27 56.4 ± 1.7 19.0 ± 1.0a (10 nM) 19.0 ± 3.4a 9.2 ± 1.1a (30 nM) 8.1 ± 1.5a
MCF-7 50.3 ± 1.5 19.1 ± 2.3a (8 nM) 18.0 ± 1.7a 11.3 ± 3.1a (20 nM) 10.9 ± 1.8a
H292 56.5 ± 0.9 39.3 ± 2.4a (15 nM) 25.6 ± 3.0a * 15.0 ± 3.0a (40 nM) 9.3 ± 2.6a
% S
ECV304 38.6 ± 1.6 44.1 ± 2.9 (10 nM) 37.1 ± 1.6 26.4 ± 3.2a (30 nM) 17.4 ± 1.7a
CAL-27 25.0 ± 1.1 33.3 ± 2.4 (10 nM) 31.0 ± 3.1 14.9 ± 1.9a (30 nM) 18.8 ± 2.6
MCF-7 26.2 ± 1.1 26.4 ± 1.4 (8 nM) 32.1 ± 2.0 29.7 ± 2.2 (20 nM) 32.1 ± 2.1a
H292 23.4 ± 0.5 23.5 ± 1.0 (15 nM) 20.0 ± 2.8 23.8 ± 2.3 (40 nM) 18.2 ± 1.8a
% G2/M
ECV304 20.2 ± 1.0 19.2 ± 1.0 (10 nM) 19.6 ± 2.8 50.2 ± 1.7a (30 nM) 62.5 ± 2.9a *
CAL-27 16.1 ± 0.7 30.4 ± 3.9a (10 nM) 32.8 ± 5.0a 55.4 ± 3.3a (30 nM) 53.7 ± 2.4a
MCF-7 20.3 ± 0.8 47.2 ± 6.1a (8 nM) 43.9 ± 1.6a 52.5 ± 4.7a (20 nM) 52.2 ± 1.2a
H292 17.8 ± 1.0 28.6 ± 1.3a (15 nM) 50.2 ± 5.0a * 53.2 ± 6.8a (40 nM) 65.9 ± 5.0a

Percentages of cells in the G1, S and G2/M phase of the cell cycle: after 24 h incubation with equitoxic concentrations of VRL and VFL; mean ± standard error.

a p < 0.05 compared to control

* p < 0.05 compared to the equitoxic concentration of VFL