Table 4.
% of cells in G2/M | ||||||
Cell line | Control | 24+0 h | 24+3 h | 24+24 h | 24+48 h | 24+72 h |
VRL | ||||||
ECV304 | 18.1 ± 0.9 | 70.3 ± 2.1a | 56.0 ± 5.8b * | 32.6 ± 1.6b | 25.1 ± 0.8c | 21.4 ± 1.5c |
CAL-27 | 14.4 ± 1.2 | 56.0 ± 1.1a | 30.7 ± 3.3b | 23.2 ± 1.3b | 21.5 ± 0.6 | 24.3 ± 2.3 |
MCF-7 | 17.8 ± 1.2 | 53.5 ± 0.9a | 28.1 ± 4.4b | 35.1 ± 3.5b | 33.1 ± 0.3 | 28.6 ± 3.2 |
H292 | 13.3 ± 0.8 | 64.0 ± 4.2a | 41.9 ± 1.2b | 40.1 ± 1.5b | 37.1 ± 1.4 | 27.1 ± 1.5c |
VFL | ||||||
ECV304 | 17.6 ± 0.9 | 47.3 ± 6.9a | 28.2 ± 2.3b | 31.8 ± 1.7b | 27.8 ± 1.1 | 23.4 ± 1.7c |
CAL-27 | 13.5 ± 0.5 | 55.7 ± 6.6a | 31.8 ± 3.6b | 24.5 ± 2.0b | 25.0 ± 0.7 | 27.6 ± 1.0 |
MCF-7 | 17.2 ± 1.0 | 53.3 ± 5.8a | 36.2 ± 3.8 | 27.8 ± 3.4b | 27.3 ± 3.1 | 29.8 ± 3.3 |
H292 | 11.9 ± 1.4 | 65.7 ± 1.1a | 39.5 ± 1.0b | 41.3 ± 2.3b | 41.0 ± 2.5 | 26.9 ± 3.9c |
Percentages of cells in the G2/M phase of the cell cycle: at different time points after a 24 h incubation with VRL or VFL; mean ± standard error.
a p < 0.05 compared to control
b p < 0.05 compared to 24+0 h
c p < 0.05 compared to 24+24 h
* p < 0.05 compared to equitoxic VFL conc.