Table 1.
Incorporation of iPS cell-derived neurons and glia after in utero transplantation
| Animal | Age | OB | CTX | SPT | TH | HT | MB | CB/BS |
|---|---|---|---|---|---|---|---|---|
| 329.1 | P0 | ++ | + | − | + | − | ++ | − |
| 329.2 | P0 | − | + | − | − | − | − | − |
| 1855.1 | P0 | − | − | − | + | + | − | − |
| 1856.3 | P0 | − | − | + | − | + | − | − |
| 1870.1 | P27 | − | ++ | + | − | ++ | − | − |
| 1865.1 | P29 | − | ++ | +++ | − | +++ | +++ | − |
| 1865.3 | P29 | − | ++ | ++ | + | +++ | − | − |
| 1857.2 | P56 | − | + | ++ | ++ | + | − | − |
| 1857.3 | P56 | − | + | ++ | − | − | − | − |
| 1857.4 | P56 | ND | ND | ND | ND | ND | +++ | − |
Cells were transplanted at E13.5, and brains were analyzed at the indicated postnatal day (P). The brains were serially sectioned, and cells incorporated into the brain parenchyma (located at least 50 μm from clusters or the ventricular wall) were counted. Indicated are the maximum number of cells on a 50-μm section from at least three sections per brain region. −, no cells; +, 1–10 cells; ++, 11–50 cells; +++, >50 cells. OB, olfactory bulb; CTX, cortex; SPT, septum; TH, thalamus; HT, hypothalamus; MB, midbrain; CB, cerebellum; BS, brain stem; ND, not done.