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. 2002 Apr;119(4):329–339. doi: 10.1085/jgp.20028519

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Copyright © 2002, The Rockefeller University Press

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Figure 4. — Effect of GC blockage on the [Ca²⁺]_i and CBF enhancement induced by ACh. Representative experiments of responses in [Ca²⁺]_i (A) and CBF (B) to 10 μM ACh obtained from either untreated cells (A, dotted line; B, open circles) or from the cells treated with 50 μM LY-83583 (A, solid line; B, closed circles). Inhibition of GC slightly attenuates the rise in [Ca²⁺]_i but completely abolishes the rise in CBF normally induced by ACh.