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. 2008 Apr;65(Suppl 1):95–106. doi: 10.1111/j.1365-2125.2008.03141.x

Figure 3.

Figure 3

Theoretical simulation of viral replication as a cascade of operational model of agonism. [TMAX] is the maximum concentration of activated target cells, which can be infected. [V] is the virus concentration. Kv is the theoretical concentration of viruses that elicits half the maximum binding to the activated receptors on the target cells. KEX is the theoretical stimulus (SX) that elicits half the maximum response (SX+1). Step 1 (Inline graphic); Step 2 (Inline graphic); Step 3 (Inline graphic); Step 4 (Inline graphic); Step 5 (Inline graphic)