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. 2008 Apr;65(Suppl 1):68–75. doi: 10.1111/j.1365-2125.2008.03138.x

Table 2.

Difference from placebo in QTc at Tmax for maraviroc and moxifloxacin

Adjusted means
End-point Comparison n Active Placebo Mean diff. 90% CI
Machine-read QTcF at median Tmax Maraviroc 100 mg vs. placebo 59 381.5 382.5 −0.93 (−2.8–0.98)
Maraviroc 300 mg vs. placebo 58 381.1 382.4 −1.3 (−3.9–1.4)
Maraviroc 900 mg vs. placebo 58 383.6 380.0 3.6 (1.5–5.8)
Moxifloxacin 400 mg vs. placebo 58 393.4 379.7 13.7 (11.5–15.8)
Manually read QTcI at median Tmax Maraviroc 100 mg vs. placebo 59 399.7 400.4 −0.72 (−3.0–1.6)
Maraviroc 300 mg vs. placebo 58 400.8 400.6 0.24 (−1.9–2.3)
Maraviroc 900 mg vs. placebo 58 402.8 399.2 3.6 (1.0–6.2)
Moxifloxacin 400 mg vs. placebo 58 412.7 398.7 14.0 (11.5–16.4)