Machine-read QTcF at median Tmax |
Maraviroc 100 mg vs. placebo |
59 |
381.5 |
382.5 |
−0.93 |
(−2.8–0.98) |
|
Maraviroc 300 mg vs. placebo |
58 |
381.1 |
382.4 |
−1.3 |
(−3.9–1.4) |
|
Maraviroc 900 mg vs. placebo |
58 |
383.6 |
380.0 |
3.6 |
(1.5–5.8) |
|
Moxifloxacin 400 mg vs. placebo |
58 |
393.4 |
379.7 |
13.7 |
(11.5–15.8) |
Manually read QTcI at median Tmax |
Maraviroc 100 mg vs. placebo |
59 |
399.7 |
400.4 |
−0.72 |
(−3.0–1.6) |
|
Maraviroc 300 mg vs. placebo |
58 |
400.8 |
400.6 |
0.24 |
(−1.9–2.3) |
|
Maraviroc 900 mg vs. placebo |
58 |
402.8 |
399.2 |
3.6 |
(1.0–6.2) |
|
Moxifloxacin 400 mg vs. placebo |
58 |
412.7 |
398.7 |
14.0 |
(11.5–16.4) |