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. 2008 Feb;172(2):345–357. doi: 10.2353/ajpath.2008.070696

Figure 5.

Figure 5

Cav-1 inhibits Cr-1 enhanced migration, invasion, and branching of EpH4 mouse mammary epithelial cells. A: Migration or invasion assay (B) of EpH4 WT, EpH4 Cav-1, EpH4 Cr-1, and EpH4 Cr-1/Cav-1 cells. OD, optical density. *P < 0.05 compared to EpH4 WT cells; **P < 0.05 compared to EpH4 Cr-1 cells. C–E: Growth in Matrigel of EpH4 WT, EpH4 Cav-1, EpH4 Cr-1, and EpH4 Cr-1/Cav-1 cells. After 1 week, colonies with branching structures were photographed (C) and counted (E). D: Magnification of EpH4 Cr-1 branching structures. *P < 0.0001 compared to EpH4 WT cells; **P < 0.0001 compared to EpH4 Cr-1 cells.