Figure 2.

Increased total T and CCR1⁺ T cells in the lung and lymph node during exacerbation. A and B: The number of total and CCR1⁺, CD4⁺, and CD8⁺ T cells was assessed in the lymph node of mice infected with RSV, sensitized to CRA, or receiving both treatments 8 hours after CRA challenge. **P < 0.001 compared to RSV. At this point both RSV and CRA/RSV treatments had significantly more total T cells in the lymph node than CRA treatment alone. ^!!P < 0.001 compared to CRA and RSV. ^!P < 0.01 compared to CRA. C and D: Total number of T cells in the lung under the same conditions as A and B. **P < 0.001. At all time points, both RSV and CRA/RSV treatments had significantly more total T cells in the lung than CRA treatment alone. C: ^!P < 0.01 compared to CRA and RSV. D: ^!P < 0.05 compared to CRA. n = three mice/group/experiment, data are pooled from three experiments.