Figure 4.

CCR1^−/− T cells are deficient in migration to sites of inflammation. A and B: CD90⁺ T cells were isolated from the lymph nodes of CCR1^−/− or wild-type mice 8 hours after antigen challenge and labeled with CFSE. Cells were transferred into wild-type mice 1 day before allergen challenge, and the number of CFSE⁺ CD4⁺ and CD8⁺ T cells per million events assessed 24 hours after antigen challenge. A: *P = 0.0081 for CD4⁺ cells and **P = 0.0085 for CD8⁺ cells. B: *P = 0.0003, n = four mice/group/experiment, data are pooled from two experiments.