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TGF-β1 induces interstitial matrix type I collagen and fibronectin expression in podocytes. A and B: RT-PCR analysis demonstrates that TGF-β1-stimulated type I collagen (A) and fibronectin (B) mRNA expression in podocytes. C: Western blot analysis shows that TGF-β1 induced fibronectin protein expression in a time- and dose-dependent manner. D: Immunofluorescence staining demonstrates the deposition and extracellular assembly of fibronectin by the control and TGF-β1-treated podocytes.
