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(A) Interdomain rotation axes within arginine kinase shown in the open substrate-free form. Arrows follow the right-hand-grip rule and are color-coded with the head indicating the moving domain, and the shaft, the fixed domain. A dotted line indicates the missing flexible loop 310–319. (B) The human ubiquitous mitochondrial creatine kinase structure (Eder et al. 2000) is colored according to the dynamic domains determined in arginine kinase.
