. 2003 Mar;12(3):447–457. doi: 10.1110/ps.0237803

Table 4A.

Percentage PPII ( P_PPII)^aat substituted position with Ala

Mutation	Position 3	Position 6	Average^a
P → A^b	28%	22%	25%
A → G^c	22%	39%	31%
P → G^d	27%	26%	27%

^aP_PPII = 1/[1 + K_conf,P(Ala)].

^bK_conf,P(Ala) = (1 − xz)/(xz/Ω − 1), where x is the ratio K_bind(Pro)/ K_bind(Ala), Ω is the ratio K_conf,P(Ala)/K_conf,P(Pro) = 7.67 (see text), and z is the contribution of proline cis/trans isomerization (1 + 0.064, see text).

^cK_conf,P(Ala) = (1 − x)/(x − Ω), where x is the ratio K_bind(Ala)/K_bind(Gly) and Ω is the ratio K_conf,P(Ala)/KK_conf,P(Gly) = 3.4 (see text).

^dK_conf,P(Ala) = K_conf,P(Gly)^e/Ω, where Ω is the ratio K_conf,P(Ala)/ K_conf,P(Gly) = 3.4 (see text).

^e Determined as described in Table 4B.