Figure 4.

(A) The first panel of this figure shows cartoon representations of the monomer forms of the GNAT superfamily members that are known to be multimeric. In each case, the conserved structural features are colored according to Wybenga-Groot et al. (1999), while the remaining parts of the molecules are represented in gray. All structures have been superimposed such that the conserved motifs are in similar orientations. Although not multimeric, NMT is included here because it contains two copies of the GNAT conserved motif. (B) The second panel shows cartoon representations of the multimeric GNAT superfamily members. Figures are colored as in (A) and are oriented such that the two copies of the GNAT motif and the C-terminal sections of the assemblies can be clearly seen.