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Reactivity of T cells from mice of various phenotypes against syngeneic MHC class II molecules of wild type animals. In experiment 1 responder lymph nodes cells from various mice were titrated and stimulated by x-irradiated spleen cells from B6 or B10.BR mice. In experiment 2, CD4+ lymph nodes cells from various animals were purified before stimulation with x-irradiated B6 stimulators. Proliferation was measured as incorporated thymidine after a 3-day culture.
