Table 2.
Points of maximum activation (WCS − WCScon) for each hormonal condition
| Brain region (Brodmann area) | L/R | Stereotaxic coordinate
|
Z value | ||
|---|---|---|---|---|---|
| x | y | z | |||
| Activation during Lupron alone | |||||
| Inferior parietal lobule (40) | R | 34 | −46 | 40 | 3.24 |
| Fusiform gyrus (19) | L | −20 | −68 | −8 | 3.56 |
| Fusiform gyrus (37) | L | −30 | −54 | −12 | 3.13 |
| Activation during Lupron plus progesterone replacement | |||||
| Inferior frontal gyrus (46) | R | 36 | 30 | 20 | 4.09 |
| Inferior frontal gyrus (46) | L | −40 | 24 | 20 | 3.09 |
| Inferior frontal gyrus (44/45) | L | −40 | 16 | 16 | 3.16 |
| Medial frontal gyrus (6) | L | −4 | 8 | 48 | 3.33 |
| Inferior parietal lobule (40) | R | 38 | −40 | 36 | 3.54 |
| Inferior parietal lobule (40) | L | −44 | −36 | 40 | 3.67 |
| Inferior parietal lobule (40) | L | −46 | −44 | 36 | 3.61 |
| Inferior parietal lobule (40) | L | −34 | −50 | 36 | 3.49 |
| Inferior temporal/lingual gyri (37/18) | L | −24 | −76 | 0 | 3.54 |
| Inferior temporal/fusiform gyri (37/19) | L | −30 | −72 | −8 | 3.42 |
| Activation during Lupron plus estrogen replacement | |||||
| Inferior frontal gyrus (46) | R | 36 | 38 | 12 | 3.74 |
| Frontal insular cortex (44/45) | L | −34 | 16 | 12 | 3.16 |
| Inferior parietal lobule (40) | R | 28 | −52 | 36 | 3.57 |
| Inferior parietal lobule (40) | R | 48 | −35 | 40 | 3.34 |
| Inferior parietal lobule (40) | L | −40 | −40 | 40 | 3.57 |
| Inferior parietal lobule (40) | L | −30 | −52 | 40 | 3.29 |
| Inferior parietal lobule (40) | L | −48 | −36 | 40 | 3.21 |
| Inferior temporal/fusiform gyri (37) | L | −40 | −48 | −12 | 4.02 |
| Fusiform gyrus/cerebellum (37) | L | −46 | −48 | −20 | 4.31 |
Stereotaxic coordinates (in mm) refer to ref. 15; x, medial-to-lateral distance from the middle (positive = right); y, anterior–posterior distance relative to the anterior commissure (positive = anterior); z, superior–inferior distance from the intercommissural line (positive = superior). L, left; R, right.