Table 4.

Divergence patterns in tteRBP and ecRBP. Classification of amino acids into core, boundary, or surface [37] allows identification of the regions which are conserved among tteRBP and ecRBP.

		Mutations
Region	Residues	All	Non-conservative*
Core	118	28	5
Boundary	58	33	16
Surface	99	58	35
Sum	275	119	56

*As defined in [36]; charge inversions are scored as non-conservative here.