Table 2.
Category | Number of sequences | % of total | p-value |
Protein synthesis/ribosome | |||
ribosome | 18 | 5.20% | 6.10E-12 |
protein biosynthesis | 19 | 5.50% | 3.60E-10 |
ribonucleoprotein complex | 25 | 7.30% | 1.80E-08 |
eukaryotic 43S preinitiation complex | 7 | 2.00% | 1.60E-05 |
eukaryotic 48S initiation complex | 6 | 1.70% | 6.00E-05 |
Protein folding | |||
posttranslational protein folding | 4 | 1.20% | 2.40E-03 |
chaperone cofactor dependent protein folding | 4 | 1.20% | 1.40E-03 |
response to unfolded protein | 6 | 1.70% | 2.70E-03 |
Immune response | |||
immunoglobulin domain | 16 | 4.70% | 4.90E-05 |
A-macroglobulin receptor | 3 | 0.90% | 1.20E-02 |
Regulatory pathway | |||
response to stress | 34 | 9.90% | 5.50E-03 |
signal transduction inhibitor | 4 | 1.20% | 6.90E-03 |
cation binding | 44 | 12.80% | 3.60E-03 |
calmodulin binding | 6 | 1.70% | 7.50E-03 |
Functional analysis of differentially expressed transcript employed DAVID tools (see Methods for detailed description). To calculate background, Affychip has been used. Some transcripts represent in more than one category. Cutoff value for category selection p < 0.05.