Table 3.

Sleep time assays

Drug (dose)	n	Genotype	Sleep time, min (mean ± SEM)
Alphaxalone (8 mg/kg)	18	Wild type	3.5  ±  0.5
	11	Null	1.6  ±  0.4*
Alphaxalone (16 mg/kg)	17	Wild type	8.6  ±  0.8
	13	Null	5.3  ±  0.7†
Pregnanolone (8 mg/kg)	18	Wild type	24.1  ±  1.8
	12	Null	14.0  ±  2.2‡
Pentobarbital (45 mg/kg)	25	Wild type	56.4  ±  3.2
	21	Null	52.2  ±  3.6
Propofol (50 mg/kg)	16	Wild type	14.1  ±  1.8
	11	Null	13.7  ±  2.5
Midazolam (25 mg/kg)	22	Wild type	14.4  ±  4.0
	16	Null	13.2  ±  4.8
Etomidate (20 mg/kg)	19	Wild type	55.3  ±  5.0
	20	Null	42.0  ±  4.5
Ketamine (150 mg/kg)	6	Wild type	40.1  ±  3.8
	6	Null	37.5  ±  2.6

*, P < 0.02; †, P < 0.01; ‡, P < 0.002.