Table 1.

Amplitude of contractile responses to bethanechol in α5–/– and wild-type mice

	Concentration of bethanechol
	1 μm	3 μm	10 μm	*3 μm
α5–/–	0.55 ± 0.15	0.71 ± 0.11	1.01 ± 0.11	0.73 ± 0.15
Wild-type	0.50 ± 0.12	0.69 ± 0.14	0.92 ± 0.16	0.69 ± 0.14

The mean contractile responses to bethanechol in α5–/– (n = 6) and wild-type (n = 20) mice. Amplitudes of responses (in grams) are given as mean ± S.D. There was no difference in response between ilea of mutant and wild-type mice in different concentrations of bethanechol (P > 0.05, t test).

^*Repeated administration of bethanechol at the end of the experiments.