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The absence of CTLA-4 does not alter thymocyte cell division. (A) Percentage of BrdU+ cells in the DP, total H57hi thymocytes, and SP (CD4SP >96% αβTCRhi; CD8SP 45% αβTCRhi) thymocytes in 11-day-old CTLA-4−/− mice and littermate controls. (B) Percentage of BrdU+ splenic αβTCR+ T cells in these animals.
