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Histological analysis. (A) Electron micrograph of normal mouse adrenocortical cells with abundant mitochondria, scant smooth endoplasmic reticulum, glycogen, and occasional lipofuscin. (×5,000.) (B) Electron micrograph of X-ALD−/o mouse adrenocortical cells with clear, presumably lipid, clefts consistent with fatty acids (indicated by arrows). (×3,000.) (C) The lipid cleft admixed with spicular lamellar material at high magnification (×15,000.).
