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EPR spectra of spin-labeled lipids (5- or 16-doxyl ketostearic acid) incorporated into mouse brain lipid micelles, with either C3 or D3. Both isomers produce a shift in the order parameter (S) of the 5-doxyl group (see Table 1), but C3 produced a greater change in S. C3 also altered the lipid (⇓)/aqueous (↓) partition factor, detected by 16-doxyl ketostearic acid, to a greater extent than D3. Both results suggest that C3 enters the lipid bilayer to a greater extent than D3.
