Figure 4. Initiation rate of a single rRNA operon (V_rrn) for various crowding scenarios in the unconstrained CGGR model.

Solid lines are predictions for the case where the rRNA chain elongation rate is assumed to be fixed at its WT value of 85 nuc/sec [17], while the dashed lines take into account the observed effect of rRNA operon copy number on rRNA elongation rates [54],[65] (see text for further details). V_rrn is given by Eq. 1. In each case considered, c_ribo was obtained by fitting to the Squires data.