Hammett plots of the reduction rate constants of
A95G (circles) and wild-type (triangles) lactate oxidase by
α-1H- (solid symbols) or α-2H- (open
symbols) forms of p-substituted
l-mandelates. The derivatives used were
dl-hydroxy-, l-methoxy-,
l-methyl-, l- and dl- H-,
l-fluoro-, l-chloro-,
l-trifluoromethyl- and l-nitro-mandelates. The
σ-parameters of p-substituted functional groups were
taken from ref. 25.