TABLE 1.
Brain region | Age | 5HT1A Receptors | 5HT2 Receptors* | 5HT Transporter | |||
---|---|---|---|---|---|---|---|
male | female | male | female | male | female | ||
Frontal/parietal cortex | PN30 | 104 ± 5 | 111 ± 2 | 125 ± 4 | 137 ± 3 | 277 ± 7 | 291 ± 10 |
PN60 | 68 ± 7 | 68 ± 7 | 116 ± 3 | 126 ± 3 | 339 ± 14 | 343 ± 9 | |
PN100 | 56 ± 2 | 49 ± 4 | 88 ± 2 | 93 ± 2 | 299 ± 9 | 287 ± 6 | |
Temporal/occipital cortex | PN30 | 138 ± 4 | 124 ± 5 | 69 ± 2 | 75 ± 2 | 199 ± 9 | 187 ± 7 |
PN60 | 99 ± 5 | 103 ± 6 | 51 ± 3 | 55 ± 2 | 207 ± 7 | 203 ± 10 | |
PN100 | 92 ± 7 | 99 ± 7 | 52 ± 2 | 61 ± 3 | 220 ± 13 | 231 ± 10 | |
Brainstem | PN30 | 38 ± 2 | 31 ± 2 | 19 ± 1 | 20 ± 1 | 276 ± 14 | 290 ± 7 |
PN60 | 22 ± 1 | 24 ± 1 | 16 ± 1 | 15 ± 1 | 251 ± 14 | 244 ± 8 | |
PN100 | 18 ± 1 | 19 ± 1 | 13 ± 1 | 14 ± 1 | 234 ± 6 | 257 ± 6 |
Data are means and standard errors obtained from 6 animals of each sex at each age.
Females significantly higher than males; main effect of sex, p < 0.0001.