Figure 2.
Gd confers delayed ischemic cardio-protection. Rats (n = 6 per group) were treated with a single dose of Gd (20 μmol/kg) via the tail vein and allowed to recover 24–120 hours. Hearts were then isolated and subjected to 30 minutes regional myocardial ischemia and 180 minutes reperfusion with Gd excluded from the coronary perfusate. Open bars represent data from saline treated rats. Solid bars represent data from Gd treated rats. LVDP, left ventricular developed pressure. Bar graphs represent the mean ± SD. * P < 0.05, Gd vs saline-treated.