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. 2008 Apr 7;336(7649):868–871. doi: 10.1136/bmj.39517.808160.BE

Table 1.

 Characteristics of included studies in systematic review of open healing or primary closure techniques after surgery for pilonidal sinus

Study Comparison No of participants in group Outcomes Notes
Open healing v midline closure:
 Al-Hassan 1990w4 Midline closure v open healing 50/50 Time to wound healing, recurrence, length of stay, return to work, wound healing rate Mean follow-up of 33 months for primary closure and 25 months for open healing. >80% follow-up
 Füzün 1994w5 Midline closure v Obeid’s technique (open) 55/55 Surgical site infection, recurrence, length of stay, return to work 84% follow-up over a mean 23 months
 Gencosmanoglu 2005w6 Midline closure v open healing (marsupialisation) 69/73 Time to wound healing, surgical site infection, recurrence, other complications, return to work Complete follow-up at 2 years
 Hameed 2001w7 Midline closure v open healing 23/20 Time to wound healing, surgical site infection, recurrence, cost, other complications 88% follow-up at minimum 14 months
 Khawaja 1992w8 Midline closure v open healing 23/23 Time to wound healing, recurrence, length of stay, return to work, other complications 100% follow-up at 1 year
 Kronborg 1985w9 Midline closure v open healing 66/33 Time to wound healing, recurrence, healing rate 98% follow-up at 36 months
 Miocinovic 1999w11 Midline closure v open healing 25/25 Recurrence 100% follow-up at 1 year
 Mohamed 2005w10 3 arms: midline closure v wide excision and open healing v limited excision and open healing 28/55 (combined open interventions) Time to wound healing, length of stay, recurrence Two open arms combined for meta-analysis, follow-up period unclear
 Rao 2001w12 Midline closure v marsupialisation (open) 29/30 Time to wound healing, pain, healing rate Follow-up period unclear
 Sondenaa 1992w2 Midline closure v open healing 60/60 Time to wound healing, surgical site infection, return to work, pain, healing rate Early report of same patient set as Sondenaa 1996w3
 Sondenaa 1996w3 Midline closure v open healing 60/60 Recurrence Final report of Sondenaa 1992w2 patient set. 100% follow-up at 3 years
Open v closed (off-midline):
 Testini 2001w1 Karydakis (off-midline closure) v open healing 60/60 Time to wound healing, recurrence, other complications, return to work, length of stay, pain, healing rate 99% follow-up at minimum 37 months
 Fazelli 2006w13 Z-plasty (off-midline closure) v open healing 72/66 Time to wound healing, recurrence, length of stay, return to work Mean follow-up 22 months
Midline closure v off-midline closure:
 Abu Galala 1999w14 Midline closure v rhomboid flap 22/24 Surgical site infection, recurrence, length of stay, return to work, wound healing rate Complete follow-up at 18 months
 Acka 2005w17 Midline closure v rhomboid flap 100/100 Surgical site infection, recurrence, length of stay, return to work, other complications, pain Complete follow-up at 23 months
 Berkem 2005w16 Midline V-Y advancement flap v off-midline V-Y advancement flap 16/18 Surgical site infection, recurrence, length of stay Complete follow-up at 30 months
 Ertan 2005w15 Midline closure v rhomboid flap 50/50 Time to wound healing, surgical site infection, recurrence, length of stay, return to work, patient satisfaction, pain Follow-up 100% at 3 months but only 65% at 1 year by phone
 Wright 2001w18 Bascom (off-midline closure) v midline closure 16/17 Recurrence, pain, length of stay Abstract, follow-up period unclear
Closed (other) v closed (other):
 Cihan 2006w19 Rhomboid flap v asymmetrical rhomboid flap 35/33 Surgical site infection, recurrence, length of stay, return to work, other complications Follow-up to 25 months, two unexplained drop-outs