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. 2008 Apr 22;118(5):1806–1814. doi: 10.1172/JCI35197

Figure 1. Reduction of blood lymphocyte counts following islet transplantation.

Figure 1

(A) Total blood lymphocyte counts (mean ± SEM) from 13 patients who received islet transplantation with anti–IL-2R induction plus rapamycin and FK506 maintenance therapy. Results are shown for the first 30 d after the first islet infusion and after the second islet infusion in patients who received 2 or more infusions (n = 11). *P < 0.05, #P < 0.01, ΧP < 0.001 versus pretransplant. (B) A single representative case (patient hSR-058-ITA-Ed08 per standard Edmonton protocol) in whom sequential counts for CD3+ T cells, CD4+ T cells, CD8+ T cells, and CD19+ B cells are shown.