Table 5.
Mouse models of colon cancer
| Model | Mm strain | N | Tumor-generating laboratory |
| Azoxymethane (AOM) | A × B | 14 | Threadgill |
| ApcMin/+ | (SWR × B6) F1 | 2 | Dove |
| ApcMin/+ | (BR × B6) F1 | 2 | Dove |
| ApcMin/+ | C57BL/6 | 5 | Groden |
| Smad3-/- | 129 | 6 | Graff |
| Smad3-/- | 129 | 7 | Coffey |
| Tgfb1-/-; Rag2-/- | C57BL/6 | 3 | Doetschman |
Tumors from four established mouse models of CRC (ApcMin/+, AOM, Smad3-/- and Tgfb1-/-; Rag2-/- were analyzed. The table provides details on the mouse strains used for the four models, as well as information on the number of samples generated per model and sample-originating laboratory.